Aurora Kinase A

**Definition:** An aurora kinase that localizes to the CENTROSOME during MITOSIS and is involved in centrosome regulation and formation of the MITOTIC SPINDLE. Aurora A overexpression in many malignant tumor types suggests that it may be directly involved in NEOPLASTIC CELL TRANSFORMATION.

**Tree numbers:** - D08.811.913.696.620.682.700.103.500 - D12.776.167.049.500 - D12.776.476.563.103.500

**Synonyms:** - Aurora A Kinases - AURKA - Aurora A Kinase - Aurora-A Kinase - AURORA2 Protein - AuroraA Kinase - Breast-Tumor-Amplified Kinase - BTAK Protein - STK15 Kinase - Aurora Kinases A - Serine-Threonine Protein Kinase 15