Intrinsically Disordered Proteins

**Definition:** Functional proteins that do not have unique, stable, folded, three-dimensional native structures or that possess non-ordered regions under physiological conditions. They are characterized by extraordinary structural flexibility and plasticity, which enable them to adopt different conformations in response to different stimuli or different interactions.

**Tree numbers:** - D12.776.481

**Synonyms:** - Intrinsically Disordered Protein - Unstructured Proteins - Natively Unfolded Proteins - Natively Unfolded Protein - Unstructured Protein