Checkpoint Kinase 2

**Definition:** Enzyme activated in response to DNA DAMAGE involved in cell cycle arrest. The gene is located on the long (q) arm of chromosome 22 at position 12.1. In humans it is encoded by the CHEK2 gene.

**Tree numbers:** - D08.811.913.696.620.682.700.145 - D12.776.476.563.145

**Synonyms:** - CDS1 Kinase - Chk2 Protein Kinase - Checkpoint-Like Protein CHK2 - PP1425 Protein Kinase - LFS2 Protein Kinase - CHEK2 Kinase - hCHK2 Kinase - Serine-Threonine-Protein Kinase CHK2 - Serine Threonine Protein Kinase Chk2