Solute Carrier Family 12, Member 3

**Definition:** Na-Cl cotransporter in the convoluted segments of the DISTAL KIDNEY TUBULE. It mediates active reabsorption of sodium and chloride and is inhibited by THIAZIDE DIURETICS.

**Tree numbers:** - D12.776.157.530.450.625.374.500 - D12.776.157.530.937.750.750 - D12.776.543.585.937.875.750

**Synonyms:** - SLC12A3 Protein - SLC12A3 Cotransporter - NCCT Protein - Na-Cl Thiazide-Sensitive Cotransporter - Na-Cl Cotransporter - Thiazide-Sensitive Sodium-Chloride Cotransporter - Na-Cl Symporter