SLC4A Proteins

**Definition:** Bicarbonate transporters that move BICARBONATE IONS in exchange of CHLORIDE IONS or SODIUM IONS across membranes. They regulate acid-base HOMEOSTASIS, cell volume and intracellular pH. Members include CHLORIDE-BICARBONATE ANTIPORTERS (SLC4A1, 2, 3, and 9); SODIUM-COUPLED BICARBONATE TRANSPORTERS (SLC4A4 and 5, 7, 8 and 10); and a sodium borate cotransporter (SLC4A11 protein).

**Tree numbers:** - D12.776.157.530.450.437 - D12.776.157.530.937.656 - D12.776.543.550.779 - D12.776.543.585.450.437 - D12.776.543.585.937.776