NPM1/RARA Long Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene (~2.1 kb) that results from a chromosomal translocation t(5;17)(q35;q21) which fuses the first 484 nucleotides of the NPM1 gene to exon 3 of the RARA gene. This rearrangement is rare and is associated with acute myeloid leukemia.

**Synonyms:** - NPM-RAR Long Form - NPM1-RARA Long Fusion Gene - NPM1::RARA Long Fusion Gene