PAX3/FOXO4 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a rearrangement involving chromosome 2 and the X chromosome which fuses the 5' portion of the PAX3 gene to the 3' portion of the FOXO4 gene. This rearrangement is associated with rare variants of alveolar rhabdomyosarcoma.

**Synonyms:** - PAX3-AFX Fusion Gene - PAX3-FOXO4 Fusion Gene - PAX3/AFX Fusion Gene - PAX3::FOXO4 Fusion Gene