Cyclin-Dependent Kinase 12

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Cyclin-dependent kinase 12 (1490 aa, ~164 kDa) is encoded by the human CDK12 gene. This protein is involved in the regulation of both RNA splicing and transcription elongation through the mediation of serine/threonine phosphorylation.

**Synonyms:** - CDC2-Related Protein Kinase 7 - Cdc2-Related Kinase with an Arginine/Serine-Rich Domain - Cdc2-Related Kinase, Arginine/Serine-Rich - Cell Division Cycle 2-Related Protein Kinase 7 - Cell Division Protein Kinase 12 - CrkRS - EC 2.7.11.22 - EC 2.7.11.23 - hCDK12