STIL wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human STIL wild-type allele is located in the vicinity of 1p32 and is approximately 64 kb in length. This allele, which encodes SCL-interrupting locus protein, is involved in signaling that promotes cellular proliferation and modulates embryonic development. A chromosomal deletion at 1p32 between this gene and the TAL1 gene is associated with T-cell acute lymphoblastic leukemia. Mutation of the gene is associated with microcephaly primary type 7.

**Synonyms:** - MCPH7 - RP1-18D14.8 - SCL-Interrupting Locus Gene - SCL/TAL1 Interrupting Locus Gene - SCL/TAL1-Interrupting Locus Gene - SIL - STIL Centriolar Assembly Protein wt Allele - TAL1 (SCL) Interrupting Locus Gene