RIGI wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RIGI wild-type allele is located in the vicinity of 9p21.1 and is approximately 71 kb in length. This allele, which encodes antiviral innate immune response receptor RIG-I protein, is involved in the recognition of viral RNA and the activation of antiviral signaling pathways. Mutations in the gene are associated with Singleton-Merten syndrome 2.

**Synonyms:** - DDX58 - DDX58 wt Allele - DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 Gene - DEAD-Box Polypeptide 58 Gene - DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 58 Gene - DEAD/H-Box 58 Gene - DExD/H-Box Helicase 58 Gene - DKFZp434J1111 - FLJ13599 - RIG-I - RIG1 - RLR-1 - RNA Helicase RIG-I Gene - RNA Sensor RIG-I wt Allele - Retinoic Acid Inducible Gene I - Retinoic Acid-Inducible Gene I - SGMRT2