SERPINF1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SERPINF1 wild-type allele is located in the vicinity of 17p13.3 and is approximately 16 kb in length. This allele, which encodes pigment epithelium-derived factor protein, plays a role in both angiogenesis and cell proliferation. Mutation of the gene is associated with osteogenesis imperfecta type 12.

**Synonyms:** - EPC-1 - OI12 - OI6 - PEDF - PIG35 - Pigment Epithelium-Derived Factor Gene - Proliferation-Inducing Protein 35 Gene - Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 wt Allele