SCN2A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SCN2A wild-type allele is located in the vicinity of 2q24.3 and is approximately 153 kb in length. This allele, which encodes sodium channel protein type 2 subunit alpha protein, plays a role in both sodium transport and membrane potential. Mutation of the gene is associated with both benign familial infantile type 3 seizures and epileptic encephalopathy early infantile type 11.

**Synonyms:** - BFIC3 - BFIS3 - BFNIS - EIEE11 - HBA - HBSCI - HBSCII - NAC2 - Na(v)1.2 - Nav1.2 - SCN2A1 - SCN2A2 - Sodium Channel, Brain Type II, Alpha Subunit Gene - Sodium Channel, Neuronal Type II, Alpha Subunit Gene - Sodium Channel, Neuronal Type II, Alpha Subunit-1 Gene - Sodium Channel, Voltage Gated, Type II, Alpha Subunit Gene - Sodium Channel, Voltage-Gated, Type II, Alpha 1 Polypeptide Gene - Sodium Channel, Voltage-Gated, Type II, Alpha 2 Polypeptide Gene - Sodium Channel, Voltage-Gated, Type II, Alpha Polypeptide Gene - Sodium Channel, Voltage-Gated, Type II, Alpha Subunit Gene - Sodium Voltage-Gated Channel Alpha Subunit 2 wt Allele