DNM2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DNM2 wild-type allele is located in the vicinity of 19p13.2 and is approximately 118 kb in length. This allele, which encodes dynamin-2 protein, is involved in both microtubule polymerization and GTPase activity. Mutation of the gene is associated with centronuclear myopathy type 1 and Charcot-Marie-Tooth disease types dominant intermediate B and 2M axonal.

**Synonyms:** - CMT2M - CMTDI1 - CMTDIB - DI-CMTB - DYN2 - DYNII - Dynamin 2 wt Allele