PROC wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PROC wild-type allele is located within 2q13-q14 and is approximately 11 kb in length. This allele, which encodes vitamin K-dependent protein C, plays a role in the negative regulation of blood coagulation. Mutation of the gene is associated with thrombophilia due to protein C deficiency.

**Synonyms:** - APC - PC - PROC1 - Protein C (Inactivator Of Coagulation Factors Va and VIIIa) wt Allele - THPH3 - THPH4