ACTB wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ACTB wild-type allele is located in the vicinity of 7p22 and is approximately 37 kb in length. This allele, which encodes actin, cytoplasmic 1 protein, plays a role in the modulation of both cell motility and cell shape. Mutation of the gene is associated with dystonia juvenile-onset and Baraitser-Winter syndrome type 1.

**Synonyms:** - Actin Beta wt Allele - Actin, Beta Gene - BRWS1 - PS1TP5BP1