MTAP wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MTAP wild-type allele is located in the vicinity of 9p21 and is approximately 230 kb in length. This allele, which encodes S-methyl-5'-thioadenosine phosphorylase protein, is involved in the metabolism of both polyamines and purines. Mutation of the gene is associated with diaphyseal medullary stenosis with malignant fibrous histiocytoma.

**Synonyms:** - BDMF - DMSFH - DMSMFH - LGMBF - MSAP - Methylthioadenosine Phosphorylase wt Allele - c86fus