CP wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CP wild-type allele is located within 3q23-q25 and is approximately 60 kb in length. This allele, which encodes ceruloplasmin protein, plays a role in iron homeostasis and neuronal survival. Mutations cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.

**Synonyms:** - CP-2 - Ceruloplasmin (Ferroxidase) wt Allele