CRBN wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CRBN wild-type allele is located in the vicinity of 3p26.3 and is approximately 31 kb in length. This allele, which encodes protein cereblon protein, is involved in ubiquitin-mediated protein degradation. Mutations are associated with autosomal recessive nonsyndromic mental retardation.

**Synonyms:** - Cereblon wt Allele - MRT2A - Mental Retardation, Non-Syndromic, Autosomal Recessive, 2A