Cytotoxic and Regulatory T-Cell Molecule

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Cytotoxic and regulatory T-cell molecule (393 aa, ~47 kDa) is encoded by the human CRTAM gene. This protein is involved in promoting natural killer (NK) cell cytotoxicity and may promote interferon-gamma (IFN-gamma) secretion by CD8+ cells.

**Synonyms:** - CD355 Antigen - CRTAM - Class I MHC Restricted T Cell Associated Molecule - Class-I MHC-Restricted T-Cell-Associated Molecule - Cytotoxic and Regulatory T Cell Molecule