I-Kappa-B Kinase

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** An enzyme complex that is involved in serine/threonine phosphorylation, inflammation and the regulation of the nuclear factor kappa-light-chain-enhancer of activated B cells protein complex. I-kappa-B kinase is comprised of three proteins, inhibitor of nuclear factor kappa-B kinase subunit alpha, beta and gamma.

**Synonyms:** - IKK - IKappaB Kinase - IkappaB Kinase Complex - Inhibitor of Nuclear Factor Kappa-B Kinase - Nuclear Factor NF-Kappa-B Inhibitor Kinase - Nuclear Factor NFKappaB Inhibitor Kinase