ALPL wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ALPL wild-type allele is located in the vicinity of 1p36.12 and is approximately 69 kb in length. This allele, which encodes alkaline phosphatase, tissue-nonspecific isozyme protein, may be involved in matrix mineralization. Mutations in this gene are associated with infantile, childhood and adult hypophosphatasias and odontohypophosphatasia.

**Synonyms:** - AP-TNAP - APTNAP - Alkaline Phosphatase, Biomineralization Associated wt Allele - Alkaline Phosphatase, Liver/Bone/Kidney Gene - HOPS - HPPA - HPPC - HPPI - HPPO - TNAP - TNS-ALP - TNSALP