C104249Level 5
TBX21 wt Allele
**Semantic type:** Gene or Genome
**Definition:** Human TBX21 wild-type allele is located in the vicinity of 17q21.32 and is approximately 13 kb in length. This allele, which encodes T-box transcription factor TBX21 protein, plays a role in the transcriptional regulation of interferon-gamma. Genetic variation is associated with susceptibility to asthma with nasal polyps and aspirin intolerance.
**Synonyms:** - T-Box 21 wt Allele - T-PET - T-bet - TBET - TBLYM
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