FGD4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FGD4 wild-type allele is located in the vicinity of 12p11.21 and is approximately 246 kb in length. This allele, which encodes FYVE, RhoGEF and PH domain-containing protein 4, is involved in regulation of the actin cytoskeleton and cell shape. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 4H (CMT4H).

**Synonyms:** - CMT4H - FGD1 Family, Member 4 Gene - FRABP - FYVE, RhoGEF and PH Domain Containing 4 wt Allele - Frabin Gene - ZFYVE6