RAD50 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RAD50 wild-type allele is located in the vicinity of 5q31 and is approximately 89 kb in length. This allele, which encodes DNA repair protein RAD50, is involved in DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Mutations in this gene are associated with Nijmegen breakage syndrome-like disorder.

**Synonyms:** - NBSLD - RAD50 (S. cerevisiae) Homolog Gene - RAD50 Double Strand Break Repair Protein wt Allele - RAD50 Homolog (S. cerevisiae) Gene - RAD50 Homolog, Double Strand Break Repair Protein Gene - RAD50, S. cerevisiae, Homolog of Gene - RAD50-2 - RAD502 - hRad50