PSENEN wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PSENEN wild-type allele is located in the vicinity of 19q13.12 and is approximately 1 kb in length. This allele, which encodes gamma-secretase subunit PEN-2 protein, is involved in the regulation of both Notch-dependent signaling and intramembrane proteolysis.

**Synonyms:** - MDS033 - MSTP064 - PEN-2 - PEN2 - Presenilin Enhancer 2 Homolog (C. elegans) wt Allele