C-1-Tetrahydrofolate Synthase, Cytoplasmic

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** C-1-tetrahydrofolate synthase, cytoplasmic (935 aa, ~102 kDa) is encoded by the human MTHFD1 gene. This protein plays a role in folic acid metabolism.

**Synonyms:** - 5,10-Methylenetetrahydrofolate Dehydrogenase, 5,10-Methylenetetrahydrofolate Cyclohydrolase, 10-Formyltetrahydrofolate Synthetase - C1-THF Synthase - Cytoplasmic C-1-Tetrahydrofolate Synthase - MTHFD1