SERPINA1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SERPINA1 wild-type allele is located in the vicinity of 14q32.1 and is approximately 14 kb in length. This allele, which encodes alpha-1-antitrypsin protein, is involved in both the regulation of proteolysis and coagulation. Mutations in this gene are associated with pulmonary disease, emphysema, and bleeding disorders.

**Synonyms:** - A1A - A1AT - AAT - Alpha1AT - PI - PI1 - PRO2275 - Protease Inhibitor 1 (Anti-Elastase), Alpha-1-Antitrypsin Gene - Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 Gene - Serine (Or Cysteine) Proteinase Inhibitor, Clade A, Member 1 Gene - Serine (or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 Gene - Serpin Family A Member 1 wt Allele - Serpin Peptidase Inhibitor Clade A (Alpha-1antiproteinase, Antitrypsin) Member 1 Gene - Serpin Peptidase Inhibitor Clade A Member 1 Gene - Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 Gene - nNIF