Sphingosine-1-Phosphate Lyase 1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Sphingosine-1-phosphate lyase 1 (568 aa, ~64 kDa) is encoded by the human SGPL1 gene. This protein plays a role in apoptosis, the elevation of stress-induced ceramide production, and the metabolism of phosphorylated sphingoid bases.

**Synonyms:** - EC 4.1.2.27 - SGPL1 - SP-Lyase 1 - Sphingosine-1-Phosphate Aldolase