AKR1C1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human AKR1C1 wild-type allele is located within 10p15-p14 and is approximately 91 kb in length. This allele, which encodes aldo-keto reductase family 1 member C1 protein, plays a role in the conversion of progesterone to its inactive form, 20-alpha-dihydroxyprogesterone, and may have a role in the transport of bile.

**Synonyms:** - Aldo-Keto Reductase Family 1, Member C1 (Dihydrodiol Dehydrogenase 1; 20-Alpha (3-Alpha)-Hydroxysteroid Dehydrogenase) Gene - Aldo-Keto Reductase Family 1, Member C1 wt Allele - C9 - DD1 - DD1/DD2 - DDH - DDH1 - H-37 - HAKRC - HBAB - MBAB