AKR1C2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human AKR1C2 wild-type allele is located within 10p15-p14 and is approximately 30 kb in length. This allele, which encodes aldo-keto reductase family 1 member C2 protein, is involved in the metabolism of steroid hormones and the inactivation of androgens. Mutations in this gene are associated with 46XY sex reversal 8.

**Synonyms:** - Aldo-Keto Reductase Family 1, Member C2 (Dihydrodiol Dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha Hydroxysteroid Dehydrogenase, Type III) Gene - Aldo-Keto Reductase Family 1, Member C2 wt Allele - BABP - DD - DD-2 - DD/BABP - DD2 - DDH2 - HAKRD - HBAB - MCDR2 - SRXY8