TNFRSF18 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TNFRSF18 wild-type allele is located in the vicinity of 1p36.3 and is approximately 3 kb in length. This allele, which encodes tumor necrosis factor receptor superfamily member 18 protein, plays a role in dominant immunological self-tolerance and may play a role in both T-cell activation and T-cell programmed cell death.

**Synonyms:** - AITR - CD357 - ENERGEN - GITR - GITR-D - Glucocorticoid-Induced TNFR-Related Gene - Tumor Necrosis Factor Receptor Superfamily Member 18 wt Allele - Tumor Necrosis Factor Receptor Superfamily, Member 18 Gene