C-Circle

**Semantic type:** Cell Component

**Definition:** A stretch of telomeric DNA where the normally guanine-rich (TTAGGG)n overhanging sequence has gaps while the cytosine-rich (AATCCC)n opposite strand remains intact. The resulting partially single-stranded telomere can adopt a circular confirmation.

**Synonyms:** - C-Circles - CC - Extrachromosomal Telomeric C-Rich DNA Circles - Partially Double-Stranded Circles of Telomeric C-Strand DNA