DIABLO wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DIABLO wild-type allele is located in the vicinity of 12q24.31 and is approximately 20 kb in length. This allele, which encodes diablo IAP-binding mitochondrial protein, is involved in the promotion of caspase-mediated apoptosis. Mutation of the gene is associated with deafness autosomal dominant type 64.

**Synonyms:** - DFNA64 - DIABLO-S - Diablo IAP-Binding Mitochondrial Protein wt Allele - Diablo, IAP-Binding Mitochondrial Protein Gene - FLJ10537 - FLJ25049 - SMAC - SMAC3 - hCG_1782202