GLIS2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GLIS2 wild-type allele is located in the vicinity of 16p13.3 and is approximately 25 kb in length. This allele, which encodes zinc finger protein GLIS2, plays a role in the modulation of both signaling and transcription. Mutation of the gene is associated with type 7 nephronophthisis.

**Synonyms:** - GLI-Similar 2 Gene - GLIS Family Zinc Finger 2 wt Allele - NKL - NPHP7 - Nephrocystin-7 Gene