TCF4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TCF4 wild-type allele is located 18q21.1 and is approximately 442 kb in length. This allele, which encodes transcription factor 4 protein, is involved in transcriptional regulation of immunoglobulin genes. Mutations in this gene are associated with Pitt-Hopkins syndrome.

**Synonyms:** - E2-2 - ITF-2 - ITF2 - PTHS - SEF-2 - SEF2 - SEF2-1 - SEF2-1A - SEF2-1B - TCF-4 - Transcription Factor 4 wt Allele - bHLHb19