Calprotectin

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A heterodimeric or heterotetrameric protein complex comprised of protein S100A8 and protein S100A9. This complex is expressed in the cytosol of neutrophils and macrophages and plays a role in multiple host defense related processes including immunomodulation, neutrophil chemotaxis and both antibacterial and antifungal responses.

**Synonyms:** - Leukocyte L1 Complex - MRP-8/MRP-14 Complex - S100A8/A9 Complex - S100A8/S100A9 Complex