KRT14 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KRT14 wild-type allele is located within 17q12-q21 and is approximately 5 kb in length. This allele, which encodes keratin, type I cytoskeletal 14 protein, plays a role in the regulation of cell morphology. Mutations in this gene are associated with dermatopathia pigmentosa reticularis, Naegeli-Franceschetti-Jadassohn syndrome, and several types of epidermolysis bullosa simplex.

**Synonyms:** - CK-14 - CK14 - EBS3 - EBS4 - K14 - Keratin 14 wt Allele - NFJ