APOB wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human APOB wild-type allele is located within 2p24-p23 and is approximately 43 kb in length. This allele, which encodes apolipoprotein B-100 protein, is involved in both transport and cellular binding of lipoprotein particles. Mutation of the gene is associated with both familial ligand-defective apolipoprotein B-100 and familial hypobetalipoproteinemia type 1.

**Synonyms:** - Apolipoprotein B (Including Ag(x) Antigen) Gene - Apolipoprotein B wt Allele - FLDB - LDLCQ4