DNase-Seq

**Semantic type:** Molecular Biology Research Technique

**Definition:** A molecular genetic technique where genome-wide sequencing is performed on DNA regions that are super sensitive to cleavage by DNase I to identify putative DNA regulatory sequences.

**Synonyms:** - DNase I Hypersensitive Sites Sequencing - DNase-Hypersensitivity (sequencing of hypersensitive sites or segments of open chromatin that are more readily cleaved by DNaseI)