POLD1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human POLD1 wild-type allele is located in the vicinity of 19q13.3 and is approximately 34 kb in length. This allele, which encodes DNA polymerase delta catalytic subunit protein, plays a role in DNA replication. Mutation of the gene may be associated with increased susceptibility to colorectal malignancies.

**Synonyms:** - CDC2 - CDC2 Homolog (S. cerevisiae) Gene - CRCS10 - DNA Polymerase Delta 1, Catalytic Subunit wt Allele - MDPL - POLD - Polymerase (DNA Directed), Delta 1, Catalytic Subunit (125kD) Gene - Polymerase (DNA Directed), Delta 1, Catalytic Subunit Gene - Polymerase (DNA) Delta 1, Catalytic Subunit Gene - Polymerase (DNA-Directed), Delta 1, Catalytic Subunit Gene - Polymerase, DNA, Delta Gene