Brilanestrant

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An orally available, nonsteroidal selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, brilanestrant binds to the estrogen receptor and induces a conformational change that results in the degradation of the receptor. This may inhibit the growth and survival of ER-expressing cancer cells.

**Synonyms:** - ARN-810 - BRILANESTRANT - GDC-0810 - RO7056118 - SERD ARN-810