Defibrotide Sodium

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** A polydeoxyribonucleotide with antithrombotic, thrombolytic, and fibrinolytic properties. Defibrotide induces the release of prostaglandin 12 and reduces the expression of adhesion molecules on endothelial cells, thereby interfering with platelet and leukocyte adhesion to the endothelium. (NCI04)

**Synonyms:** - DEFIBROTIDE SODIUM - Defibrinotide - Defibrotide - Defitelio - Fraction P - Noravid - Prociclide - defibrotide