MAP2K2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MAP2K2 wild-type allele is located in the vicinity of 19p13.3 and is approximately 34 kb in length. This allele, which encodes dual specificity mitogen-activated protein kinase kinase 2 protein, is involved in both MAPK and toll-like receptor signaling pathways. Mutation of the gene is associated with cardiofaciocutaneous syndrome.

**Synonyms:** - MAPKK2 - MEK2 - MKK2 - Mitogen-Activated Protein Kinase Kinase 2 wt Allele - PRKMK2