Mothers Against Decapentaplegic Homolog 1

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Mothers against decapentaplegic homolog 1 (465 aa, ~52 kDa) is encoded by the human SMAD1 gene. This protein plays a role in regulating the action of bone morphogenic proteins in cell growth, apoptosis, morphogenesis, development and immune responses.

**Synonyms:** - MAD Homolog 1 - MAD, Mothers Against Decapentaplegic Homolog 1 - MAD, Mothers Against Decapentaplegic Homolog 1 (Drosophila) - Mad-Related Protein 1 - Mothers Against DPP Homolog 1 - SMAD, Mothers Against DPP Homolog 1 (Drosophila) - TGF-Beta Signaling Protein 1 - Transforming Growth Factor-Beta Signaling Protein 1 - Transforming Growth Factor-Beta-Signaling Protein 1