C1075Level 5
Doxorubicin-DNA Complex
**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance
**Definition:** A complex comprised of Doxorubicin linked to DNA to enhance the topoisomerase II-mediated interaction with the DNA base pairs and reduce cardiotoxicity associated with anthracyclines. (NCI)
**Synonyms:** - Adriamycin-DNA Complex
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