CYP3A Gene Locus

**Semantic type:** Gene or Genome

**Definition:** Human CYP3A gene locus is located within 7q21.3-q22.1 and is approximately 218 kb in length. This locus includes four protein-encoding genes, CYP3A4, CYP3A5, CYP3A7 and CYP3A43, and two pseudogenes, CYP3A5P1 and CYP3A5P2. The protein-encoding genes are involved in drug metabolism and the biosynthesis of cholesterol, steroids and other lipids.

**Synonyms:** - CYP3 - CYP3A - CYP3A - Cytochrome P450 Family 3 Subfamily A Gene Locus - Cytochrome P450, Family 3, Subfamily A Gene Locus - Cytochrome P450, Subfamily IIIA (Niphedipine Oxidase) Gene Locus