PROS1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PROS1 wild-type allele is located in the vicinity of 3q11.2 and is approximately 101 kb in length. This allele, which encodes vitamin K-dependent protein S, is involved in the regulation of coagulation. Mutations in this gene are associated with both autosomal dominant and autosomal recessive thrombophilia due to protein S deficiency.

**Synonyms:** - PROS - PS21 - PS22 - PS23 - PS24 - PS25 - PSA - Protein S (Alpha) wt Allele - Protein S, Alpha Gene - THPH5 - THPH6