Fosfestrol

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The diphosphate ester of a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration.

**Synonyms:** - (E)-4,4'-(1,2-ethenediyl)-bisphenol bis(dihydrogen phosphate) - Alpha,alpha'-diethyl-4,4'-stilbenediol Diphosphoric Acid Ester - DESP - Diethyldihydroxystilbene Diphosphate - Diethylstilbestrol 4,4'-Diphosphoric Ester - Diethylstilbestrol Diphosphate - Diethylstilbestryl Diphosphate - FOSFESTROL - Fosfestrol Sodium Phosphoestrolum - Honvan - Honvol - ST-52 - Stilbestrol Diphosphate - Stilboestrol Diphosphate - Stilphostrol - Stilphostrol