CFTR wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CFTR wild-type allele is located in the vicinity of 7q31.2 and is approximately 203 kb in length. This allele, which encodes cystic fibrosis transmembrane conductance regulator protein, plays a role in the transport of chloride ions. Mutation of the gene is associated with cystic fibrosis and congenital bilateral absence of the vas deferens.

**Synonyms:** - ABC35 - ABCC7 - CF - CFTR/MRP - Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) wt Allele - Cystic Fibrosis Transmembrane Conductance Regulator, ATP-Binding Cassette (Sub-Family C, Member 7) Gene - MRP7 - TNR-CFTR - dJ760C5.1