MKRN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MKRN1 wild-type allele is located in the vicinity of 7q34 and is approximately 27 kb in length. This allele, which encodes E3 ubiquitin-protein ligase makorin-1 protein, plays a role in post-translational protein ubiquitination. A fusion of this gene and the BRAF gene may be associated with pilocytic astrocytoma.

**Synonyms:** - Makorin Ring Finger Protein 1 wt Allele - RING Finger Protein 61 Gene - RNF61